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Alpha blockers (see Table 2) are most commonly prescribed to treat high blood pressure and BPH. That’s because the prostate and bladder are rich in alpha receptors.By blocking these cellular structures, alpha blockers help relax muscles in the prostate and urinary tract, allowing urine to flow more freely.Of participants taking the drug, 60% had a greater than 50% drop in their average symptom score, compared with 37% for participants taking a placebo.A subsequent study by the same researchers concluded that the beneficial effect lasted up to 38 weeks.They are both associated with an infection of the prostate.Acute prostatitis begins abruptly with high fever, chills, joint and muscle aches, and profound fatigue.A major difficulty is that in most cases doctors are unable to definitively diagnose CP/CPPS or identify a causative agent.
Known as the “three A’s,” traditional treatments for chronic nonbacterial prostatitis/chronic pelvic pain syndrome are antibiotics, anti-inflammatory medications, and alpha blockers. For starters, few men with CP/CPPS test positive for bacterial infection.
The National Institute of Diabetes and Digestive and Kidney Diseases, part of the National Institutes of Health, classifies prostatitis into four categories, each with its own treatment approach (see Table 1).
Category I and Category II refer to acute and chronic bacterial prostatitis, respectively.
Yet only one controlled study supports the use of NSAIDs as the primary treatment for CP/CPPS.
Most doctors agree that if NSAIDs are used, they should be taken for a limited period of time, to control pain, and preferably with another medication, such as an alpha blocker.